What medicine is used to treat fatty liver?
In recent years, fatty liver has become one of the common chronic liver diseases in the world, and with changes in lifestyle, the incidence rate is increasing year by year. The treatment of fatty liver requires not only lifestyle intervention, but sometimes also medication assistance. This article will combine the hot topics and hot content on the Internet in the past 10 days to introduce you to the drug treatment plan for fatty liver in detail.
1. Classification and treatment principles of fatty liver
Fatty liver is divided intoNon-alcoholic fatty liver disease (NAFLD)andAlcoholic Fatty Liver Disease (AFLD)Two major categories. Treatment principles include: controlling weight, improving metabolism, reducing liver fat deposition, and anti-inflammatory and liver protection. The following are common drug treatment options.
| drug type | Representative medicine | Mechanism of action | Applicable people |
|---|---|---|---|
| lipid-lowering drugs | Atorvastatin, fenofibrate | Lower blood lipids and reduce liver fat deposition | Fatty liver patients with hyperlipidemia |
| insulin sensitizer | Metformin, pioglitazone | Improve insulin resistance and reduce liver inflammation | Fatty liver patients with diabetes |
| Antioxidants | Vitamin E, silymarin | Reduce oxidative stress and protect liver cells | Non-alcoholic steatohepatitis (NASH) patients |
| Hepatoprotective drugs | Glycyrrhizic acid preparations, reduced glutathione | Anti-inflammatory, repair liver cell membrane | Patients with abnormal liver function |
2. Recent hot research and new drug progress
In the past 10 days, the medical community has made new progress in the treatment of fatty liver:
| research topic | Key findings | Source |
|---|---|---|
| GLP-1 receptor agonists | Semaglutide can significantly improve liver fibrosis in NASH patients | New England Journal of Medicine |
| FXR agonists | Obeticholic acid shown to reduce liver fat in clinical trial | "Hepatology" |
| Intestinal microecological regulation | Probiotics combined with dietary intervention can improve fatty liver | "Nature" sub-journal |
3. Combination of lifestyle intervention and drug treatment
Drug treatment needs to be carried out under the guidance of a doctor and must be coordinated with lifestyle adjustments:
4. Precautions for drug treatment
1.Personalized medicine:Medications are selected based on patient comorbidities (such as diabetes, hyperlipidemia).
2.Regular monitoring:Check liver function, blood lipids, blood sugar and other indicators every 3-6 months.
3.Avoid overusing hepatoprotective drugs:Some hepatoprotective drugs may mask the condition and should be used under the guidance of a doctor.
5. Summary
The drug treatment of fatty liver needs to be selected according to the patient's specific condition. Recent research on new drugs such as GLP-1 receptor agonists and FXR agonists has provided patients with more choices. However, it should be noted that drug treatment must be combined with lifestyle intervention to achieve the best results. If you have problems related to fatty liver, it is recommended to seek medical treatment promptly and develop a personalized treatment plan.
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